For anyone with dandruff, flaking, an itchy scalp, or an oily scalp that flakes — it's positioned as a medicated, symptom-targeting shampoo rather than a general cleansing shampoo, and its tags mark it for all hair types, for both men and women. It isn't tagged or marketed as color-safe the way some other Biolage shampoos are, so color-treated hair isn't specifically called out as a use case for this one. It's a retail, over-the-counter product (pyrithione zinc is an FDA drug-monograph active ingredient), not a professional in-salon treatment.

What sets this apart from a basic dandruff shampoo is layering a mild exfoliant (glycolic acid) on top of the antifungal active, meant to help clear the flake and product buildup that pyrithione zinc alone doesn't address, plus a fermented tea blend included for its calming effect on irritated scalps. It's worth choosing over a plain zinc-pyrithione shampoo specifically when flaking comes with visible buildup or general scalp discomfort, not just the dandruff itself.

Apply to wet hair and scalp, massage into a lather so the active ingredient makes contact with the scalp rather than just the hair, then rinse thoroughly. Biolage recommends regular, consistent use — not just occasional washes — to reduce visible flaking and keep the scalp feeling balanced.

• Combines three anti-dandruff mechanisms — pyrithione zinc (the antifungal/antimicrobial active), glycolic acid (mild exfoliation to clear flake buildup), and a fermented tea blend (antioxidant/soothing) — rather than relying on the active alone.
• Brand states scalps feel balanced for up to 72 hours with regular use, longer than a single wash cycle.
• Certified cruelty-free (Leaping Bunny) and formulated without parabens.

• Uses sulfate cleansers (SLES/SLS) as its base, so it can be more drying on an already-sensitive or eczema-prone scalp than a sulfate-free medicated option.
• Contains methylisothiazolinone, a preservative recognized as a contact allergen for some people.
• Brand copy calls it silicone-free, but an independently sourced ingredient list shows dimethicone present — worth checking your specific bottle's printed ingredient panel if that matters to you.